伊博加因如何改变生活

伊博加因如何改变生活

LSD,魔术蘑菇,DMT,MDMA(妈妈警告过的所有东西)现在已被证明是治疗多种精神健康状况的关键。 There is one name that may be unfamiliar to most however, and that is ibogaine.然而,有一个名字可能是大多数人都不熟悉的,那就是伊博加因。

您可能还已经看到它包含在美国组织的精神活性植物列表中 非自然化 希望被判刑。 因此,第一个线索是,这是一种具有精神活性的植物……但是,如果它将成为一种新的奇效药物,我们需要对此了解更多的信息。 它有叶子。 Having been touted as an addiction cure, and a potential game changer in the handling of the被吹捧成瘾的治疗方法,并可能在处理毒品问题上改变游戏规则 阿片类药物危机在美国,好像很高 是时候就伊博加因进行自我教育了。 

它是什么?

Ibogaine is a psychoactive substance extracted from the root barks of the iboga tree.伊博加因是从伊博加树的根皮提取的一种精神活性物质。 A naturally occurring compound, it can also be found in all plants of the天然存在的化合物,也可以在植物的所有植物中找到 夹竹桃科。  It was first used by the Pygmy tribes of Central Africa, who then passed the knowledge of its uses to the Bwiti tribe of Gabon.它最初是由中非the格米人部落使用的,然后将其用途的知识传给了加蓬的布瓦提部落。 This tribe then passed on the information to French explorers, who then brought it to Europe in around 1899-1900.然后,该部落将该信息传递给法国探险家,然后法国探险家在XNUMX-XNUMX年左右将其带到了欧洲。 The African tribes used it for medicinal, therapeutic and ceremonial purposes.非洲部落将其用于医药,治疗和礼仪目的。 In France it was marketed as在法国,它以 朗伯烯 for use as a stimulant.用作兴奋剂。 In low doses the psychoactive qualities of the substance are minor, but it is effective at staving off tiredness.在低剂量下,该物质的精神活性较弱,但可有效消除疲劳。

By the 1960s however, it became illegal.但是到1950年代,它已成为非法。 In the 60s and 'XNUMXs some scientists在XNUMX和XNUMX年代,一些科学家 民政事务总署 一直在使用该化合物作为抗抑郁药,但这将是一个特殊情况,标志着其作为抗成瘾工具的潜力。

意外治愈

1962年,19岁的海洛因使用者 霍华德·洛索夫 got hold of some ground iboga.掌握了一些地面iboga。 In search of a new high, little did he know he'd come around from his trip, (in his words)为了寻找新的高潮,他几乎不知道自己会从旅途中回来,(用他的话来说) “直行。” Fascinated, he encouraged six of his friends, also heroin addicts, to try the substance.他着迷,鼓励他的六个朋友(也是海洛因成瘾者)尝试使用这种物质。 Five out of six of them immediately quit their drug use.其中六分之五立即戒烟。 From that moment on, Lotsof became a lifelong advocate of the substance.从那一刻起,洛索夫就成为该物质的终生拥护者。 He facilitated the treatment of many addicts, and began a他促进了许多成瘾者的治疗,并开始了 基础。 FDA批准了ibogaine的抗成瘾特性的临床试验。 Sadly, this stalled and ultimately did not come to pass, due to financing and contractual issues.可悲的是,由于融资和合同问题,这种情况陷入停滞,最终没有实现。 Ibogaine remained illegal in the US.伊博加因在美国仍然是非法的。 Lotsof died in 2010, sadly too early to see the changes now coming into being.洛索夫于XNUMX年去世,可悲的是,现在看到这种变化已经为时过早。

治疗费用昂贵

但是,伊博加因治疗 具有 been available in a few locations since the '90s, mainly down to Lotsof's advocacy.自5000年代以来在少数几个地方都可以使用,主要取决于Lotsof的倡导。 These clinics are largely in Mexico but it is also legal in South Africa, Brazil and New Zealand.这些诊所主要在墨西哥,但在南非,巴西和新西兰也合法。 Although, only when administered by a licensed professional.虽然,仅当由持牌专业人员管理时。 Unfortunately, at between $10000 and $XNUMX dollars, it is prohibitively expensive for most.不幸的是,在XNUMX美元到XNUMX美元之间,对于大多数人来说,它的价格过高。 Regardless, people from all over the world travel to these locations with the hope of treating their addictions.无论如何,来自世界各地的人们到这些地方旅行都是希望能治愈他们的成瘾。 

它是如何工作的?

In traditional rehabilitation settings, withdrawals are alleviated with further drugs, in a process known as 'substitution' therapy.在传统的康复环境中,通过称为“替代”疗法的过程可通过进一步药物缓解戒断症状。 Ibogaine is said to tackle the addiction itself, rather than replacing one substance with a bunch of others.据说伊博加因本身就解决了成瘾问题,而不是用一堆其他物质代替一种物质。 Dana Beal, an ibogaine activist, explains that these 10 hour journeys are not like the psychedelic trips that many are familiar with.易卜生活动家达娜·比尔(Dana Beal)解释说,这XNUMX个小时的旅程不像许多人所熟悉的迷幻之旅。

她说;

“它不是迷幻剂,如LSD。 “你闭上眼睛,进入一个醒着的梦。 You're paralyzed because you can't summon the will to move.您瘫痪了,因为您无法召集搬迁的意愿。 You just want to lie in a quiet room, left alone to review your lifetime of memories.”您只想躺在一个安静的房间里,一个人呆着,回顾一下自己的一生。”

Researchers are still not quite sure what makes ibogaine the 'anti-drug'.研究人员仍不太确定是什么使伊博加因成为“反毒品”。 However, a trickle of clinically approved studies are finally appearing.但是,最终获得了一系列经过临床批准的研究。 One of which, performed in 2018 and published in其中一项于XNUMX年演出并于 美国药物和酒精滥用杂志 发现在进行伊博加因治疗后,有50%的患者在接受30个月的检查后表示XNUMX天内未使用阿片类药物。 这项研究虽然规模较小,但反对使用美沙酮,可洛平和丁丙诺啡的传统方法。 多达一半的患者无法完成此治疗。  

所以有什么问题?

阻碍ibogaine迈向合法化的一个因素是 已可以选用 been deaths recorded during treatment.记录了治疗期间的死亡人数。 However, the 19 fatalities recorded from over 4000 treatments worldwide, have largely been avoidable.但是,在全球范围内可以避免的XNUMX多次治疗记录的XNUMX起死亡事故是可以避免的。 Dr Ken Alper, a professor of neurology and psychiatry at NYU school of medicine explains most were the result of improper supervision or un-diagnosed health conditions.纽约大学医学院神经病学和精神病学教授肯·阿尔珀(Ken Alper)博士解释说,大多数原因是监管不当或健康状况未得到诊断。 Nonetheless, this marks out ibogaine as too risky for the FDA to really get behind.但是,这表明依博加因对FDA而言实在是太冒险了。 Additionally, as a naturally occurring substance, Big Pharma can't patent it and line their pockets with the profit, which negates their interest.此外,作为天然物质,Big​​ Pharma无法申请专利,也无法从利润中赚钱,这抵消了他们的兴趣。 Alper is however, working with但是,Alper正在与 心灵药业公司, a Canadian company, to research a synthetic derivative called 18-methoxycoronaridine (18-mc).加拿大的一家公司,研究一种名为XNUMX-甲氧基Coronaridine(XNUMX-mc)的合成衍生物。 This has been synthesised to remove the risks and hallucinations associated with ibogaine.已经合成了这种物质,以消除与伊博加因有关的风险和幻觉。 

治疗永远没有风险

Alper firmly believes that addiction should be seen as a chronic, though treatable, illness.阿尔珀坚信,成瘾应被视为一种慢性病,尽管可以治愈。 In many cases, the treatment for a disease is not without risk.在许多情况下,疾病的治疗并非没有风险。 He explains;他解释道;

“是的,依博加因存在危险,但是未经治疗的依赖性的严重性如何? If you're developing a cancer treatment like chemotherapy, you're going to tolerate serious side effects.如果您正在开发像化学疗法这样的癌症治疗方法,那么您将可以忍受严重的副作用。 Addiction being a life threatening condition is not fully factored into our tolerance for risk.”成瘾是威胁生命的疾病,并没有完全纳入我们对风险的承受能力。”

也许其中一个要素 holding ibogaine research back is that we are only just beginning to understand addiction as illness to be treated, rather than as a pathology.抑制ibogaine研究的原因是,我们才刚刚开始将成瘾理解为要治疗的疾病,而不是病理学。 However, as psychedelic plants and their phenomenal results continue to be researched, maybe, just maybe, minds will be opened.但是,随着对迷幻植物及其惊人结果的不断研究,也许会打开思路。 In fact, in Chicago's recent successful petition to decriminalise natural psychedelics实际上,在芝加哥最近成功的请愿书中,将自然迷幻药非犯罪化 (包括伊博加因) 他们直接引用了该城市目前正在遭受的阿片类药物危机作为其必要性的原因。 

那里有很多信息...

There is a strong selection of media about ibogaine to choose from if you want to learn more.如果您想了解更多信息,可以选择很多有关ibogaine的媒体。 For example, recently at Wholecelium HQ, we hunkered down例如,最近在Wholecelium总部, (有距离!) 观看2019年的纪录片 加药. The film follows a long-term addict Adrianne and her rocky journey to recovery via psychedelic plant medicines, including iboga.这部电影讲述了一个长期的瘾君子阿德里安(Adrianne)和她通过迷幻药(包括iboga)康复的艰难旅程。 Both fascinating and emotionally hard-hitting, it gave a window into the mysterious ways in which these substances work.既令人着迷又在情感上令人难以抗拒,它为这些物质发挥作用的神秘方式提供了一个窗口。 

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